Anti-GTF2A1 Antibody

Raised in rabbit against the GTF2A1 transcription factor subunit, this unconjugated polyclonal antibody from Antibodies.com recognizes General Transcription Factor IIA Subunit 1, a component of the TFIIA complex that supports RNA polymerase II transcription initiation in human cells.

The antibody is supplied as 100 µL of reagent in a vial and is validated for Western blot and immunohistochemistry workflows on human tissue samples. Because it is polyclonal, the reagent binds several independent epitopes on the GTF2A1 target, which can be useful for detecting lower-abundance antigen or for capturing the protein under partial denaturation conditions.

The unconjugated format leaves the choice of reporter label, secondary antibody, or signal amplification system to the end user, so the same antibody can be paired with HRP, fluorescent, or biotin-based detection depending on the assay. Researchers working on basal transcription machinery, transcription initiation factor recruitment, or chromatin-associated regulatory complexes commonly use anti-GTF2A1 reagents to probe TFIIA subunit expression, subcellular localization, and interaction partners in nuclear extracts and fixed tissue sections.