Anti-GSTP1 Antibody

Raised in rabbit against the glutathione S-transferase P1 (GSTP1) target, this unconjugated polyclonal IgG preparation is supplied by Antibodies.com as a 100 µl vial for immunoassay workflows. GSTP1 is a Phase II detoxification enzyme that catalyzes the conjugation of reduced glutathione to electrophilic substrates, and it is widely investigated as a biomarker in prostate, breast, and hepatocellular carcinoma studies where promoter hypermethylation and altered protein expression are frequently examined.

The reagent has been validated for western blot (WB), immunohistochemistry (IHC), immunofluorescence (IF), and flow cytometry (FC), and it cross-reacts with both human and mouse samples, enabling translational research across cell line panels and rodent tissue models. The unconjugated format allows users to pair the antibody with their own secondary detection chemistries — HRP, fluorophore conjugates, or biotin — depending on the application. The antibody recognizes the full-length GSTP1 protein, which migrates at approximately 23 kDa on SDS-PAGE, a useful reference when interpreting western blot bands.

Researchers commonly apply this reagent to study oxidative stress responses, chemotherapeutic resistance mechanisms, and tumor suppressor pathway activity in vitro and in vivo. Aliquot upon receipt and store at -20°C to preserve reactivity across multiple freeze-thaw events. The polyclonal format supports assays where epitope diversity improves detection of denatured or partially degraded target protein.