Anti-GSTM4 Antibody

This polyclonal antibody from Antibodies.com targets GSTM4 (Glutathione S-Transferase Mu 4), a cytosolic enzyme belonging to the Mu-class of phase II detoxification proteins. The antibody is supplied as 100 µl of liquid at 1 mg/ml, formulated in PBS with 0.1% Sodium Azide and 50% glycerol as a cryoprotectant. Raised in rabbit, the unconjugated reagent is validated for Western Blot (WB) and Immunohistochemistry (IHC) workflows and shows reactivity with both Human and Mouse samples.

GSTM4 catalyzes the conjugation of reduced glutathione to a diverse array of hydrophobic electrophiles and is notable for its role in metabolizing J-series prostaglandins, including 15-deoxy-Δ12,14-prostaglandin J2, linking it to prostaglandin-dependent signaling and apoptotic regulation in cancer and inflammation research. Researchers commonly deploy this reagent to probe GSTM4 expression in tissue sections and cell lysates, particularly in studies of prostate cancer progression and oxidative-stress responses. For handling, refrigerate upon arrival; for longer-term storage, aliquot and freeze the vial to minimize freeze-thaw cycles and preserve antibody activity for research use only.