Anti-GSTM2 Antibody

This polyclonal primary antibody targets GSTM2 (Glutathione S-Transferase Mu 2), a cytosolic Phase II detoxification enzyme that catalyzes conjugation of glutathione to a wide spectrum of electrophilic substrates. Produced in rabbit and supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the reagent is validated for Western blot detection of the human, mouse, and rat GSTM2 protein.

Mu-class glutathione S-transferases such as GSTM2 contribute to cellular responses against oxidative and xenobiotic stress and are widely studied in the context of chemoprotection, drug metabolism, and tumor biology. The unconjugated format allows direct use with HRP- or fluorophore-labeled secondary reagents in standard immunoblotting workflows, supporting detection of endogenous GSTM2 expression across cultured cells, tissue lysates, and recombinant samples.

Each vial contains 100 µL of antibody, with the glycerol-containing buffer protecting the protein during routine freeze-thaw handling. Researchers investigating GST isoform regulation, chemoresistance mechanisms, or comparative detoxification capacity in mammalian models can integrate this reagent from Antibodies.com into existing Western blot protocols without extensive dilution optimization for most standard lysate preparations.