Anti-GSN Antibody

This polyclonal antibody from Antibodies.com targets GSN (gelsolin), a calcium-regulated actin-binding protein that severs and caps filamentous actin and supports cytoskeletal remodeling in motile cells. The reagent is raised in rabbit, isotype IgG, and is supplied unconjugated in a 100 µl vial, providing enough material for routine Western blot, immunohistochemistry, and flow cytometry experiments without immediate aliquoting. The antibody is reactive against human, mouse, and rat samples, supporting cross-species cytoskeletal and cell-signaling studies. Gelsolin is widely investigated in cancer invasion, neuronal injury response, and inflammatory cell migration, making this reagent a practical choice for laboratories working on actin dynamics, tumor microenvironment biology, or neurodegeneration models that require a consistent pan-species detection reagent. Researchers typically pair this primary with horseradish peroxidase- or fluorophore-conjugated secondaries for chemiluminescent immunoblot detection or chromogenic IHC visualization. Refrigerated storage and protection from light preserve activity through the working shelf life, and short-term handling on ice during staining protocols helps maintain the IgG fraction. Intended for research use only, the antibody enables laboratory investigation of gelsolin expression patterns across tissues and disease models.