Anti-GSN Antibody

A rabbit polyclonal antibody targeting gelsolin (GSN), an actin-binding cytoskeletal regulator that severs and caps actin filaments during cell motility, apoptosis, and inflammatory signaling. Validated for Western blot and immunofluorescence workflows, this unconjugated IgG reagent from Antibodies.com detects human, mouse, and rat gelsolin isoforms in fixed cells and lysate preparations.

Shipped as a 100 µl aliquot, the antibody supports multiple immunostaining and immunoblotting experiments. Researchers investigating actin turnover, tumor cell migration, or neurodegenerative cytoskeletal changes can apply the broad species reactivity to compare gelsolin expression patterns across human biopsy samples and corresponding rodent model tissues. The unconjugated format allows downstream pairing with user-selected secondary detection reagents, including HRP, fluorophore, or biotin conjugates chosen for the specific assay platform.

Produced in rabbit host, the polyclonal preparation yields broad epitope coverage that improves recognition of multiple gelsolin isoforms and post-translationally processed fragments. IgG isotype consistency supports compatibility with common anti-rabbit secondary antibodies used in fluorescence microscopy, chemiluminescent western blotting, and chromogenic detection systems.