Anti-GSK3B Antibody [Assigned #A10877]

GSK3B (Glycogen Synthase Kinase 3 Beta) is a constitutively active serine/threonine kinase that regulates glycogen metabolism, Wnt/β-catenin signaling, and tau phosphorylation. This rabbit monoclonal IgG reagent from Antibodies.com, assigned clone #A10877, is supplied as a 50 µl vial of unconjugated antibody validated for western blot, immunohistochemistry, and immunofluorescence workflows on human and mouse samples.

The antibody recognizes the catalytic domain region of GSK3B and is commonly used to probe phosphorylation-dependent signaling in neuronal, metabolic, and oncology research contexts. Because it is unconjugated, it pairs cleanly with HRP-, fluorophore-, or biotin-labeled secondary reagents for detection on membranes or fixed tissue sections. Researchers studying insulin signaling, Alzheimer's-related tau pathology, and tumor cell proliferation rely on this reagent for reproducible band detection in WB and crisp nuclear or cytoplasmic staining in IF and IHC.