Anti-GSK3B Antibody [Assigned #A10877]

This unconjugated rabbit monoclonal antibody specifically targets GSK3B (Glycogen Synthase Kinase 3 Beta), a constitutively active serine/threonine kinase best known for its role in glycogen metabolism and the Wnt signaling pathway. Supplied by Antibodies.com as a 200 µl liquid format, the reagent is validated for three core research workflows: Western blot detection of total and phosphorylated GSK3B, immunohistochemistry on formalin-fixed tissue sections, and immunofluorescence imaging in cultured cells. The antibody is of the IgG isotype and has been raised in rabbit, providing a single-epitope reagent for studies of insulin signaling, neurobiology (including Tau phosphorylation relevant to Alzheimer's research), and oncology where GSK3B contributes to proliferation and apoptosis pathways. Cross-reactivity has been confirmed in human and mouse samples, making it a practical choice for both patient-derived tissues and standard mouse model systems. The unconjugated format gives researchers full flexibility to pair it with their own secondary detection reagents, HRP-conjugates, or fluorescent labels depending on the assay. Intended for research use only, this antibody supports pathway-focused studies on glycogen synthase regulation, beta-catenin signaling, and downstream substrates such as Tau and glycogen synthase.