Anti-GSK3b (Ab-9) Antibody

The Antibodies.com rabbit polyclonal reagent targets glycogen synthase kinase 3 beta (GSK3b), a constitutively active serine/threonine kinase that phosphorylates glycogen synthase and regulates glucose homeostasis, Wnt/β-catenin signaling, and microtubule dynamics in neurons. Raised against the Ab-9 epitope region of human GSK3b, this unconjugated primary antibody is supplied as a 100 µl liquid aliquot and is validated for western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF) workflows.

Cross-reactivity has been demonstrated against human, mouse, and rat samples, making the reagent useful across cell-line, primary-culture, and tissue-section studies of insulin signaling, neurobiology, and oncogenic pathways where GSK3b activity is implicated. The polyclonal format allows recognition of multiple epitopes on the approximately 46 kDa kinase, which can be advantageous when probing denatured lysates or fixed specimens where a single monoclonal epitope may be masked by fixation-induced cross-linking.

Aliquot the vial upon receipt to limit freeze-thaw cycles and store at -20 °C in working volumes; the unconjugated format gives end users full flexibility to conjugate the reagent to HRP, biotin, fluorophores, or gold particles depending on the detection chemistry of their assay. Each vial contains 100 µl of ready-to-use reagent compatible with standard immunodetection protocols.