Anti-GSK3α / β Antibody

Raised in rabbit against glycogen synthase kinase-3 alpha and beta, this unconjugated polyclonal reagent from Antibodies.com is supplied as 100 µl of antiserum for western blot, immunohistochemistry, and ELISA workflows. The antibody recognizes endogenous GSK3α and cross-reacts with the closely related GSK3β isoform, supporting studies of insulin signaling, Wnt pathway activity, neuronal phospho-regulation, and other kinase-driven processes in human, mouse, and rat samples. As an unconjugated primary antibody, it pairs with the researcher's choice of labeled secondary detection reagent, and the polyclonal format broadens epitope coverage across the conserved kinase domain. Researchers commonly apply this reagent to investigate tau phosphorylation, glycogen metabolism, and oncogenic signaling pathways where GSK3 activity plays a regulatory role. Shipped in a vial, the reagent should be stored refrigerated; aliquoting is recommended to limit repeated freeze-thaw cycles and preserve binding activity over the working shelf life.