Anti-GSDMB Antibody

Produced in rabbit as a polyclonal IgG preparation, this unconjugated primary antibody recognizes gasdermin B (GSDMB), a member of the gasdermin protein family linked to inflammatory cell death and pyroptotic pore formation in the plasma membrane.

GSDMB is expressed in epithelial tissues with notable enrichment in the gastrointestinal and respiratory tracts, and polymorphisms in the GSDMB locus have been associated with asthma susceptibility as well as tumor progression in several solid cancer types. The Antibodies.com antibody is validated for Western Blot and was raised to react with human, mouse, and rat samples, supporting translational studies that compare GSDMB expression across these species. Each vial contains 200 µL of unconjugated reagent, allowing flexible secondary antibody pairing for chemiluminescent or fluorescent detection. The product is intended for research use only.