Anti-GRM3 Antibody

Glutamate Metabotropic Receptor 3 (GRM3, also called mGluR3) is a class C G protein-coupled receptor that mediates presynaptic and glial inhibition of glutamatergic neurotransmission across the central nervous system. The Antibodies.com polyclonal reagent raised in rabbit supports Western blot verification of receptor size from cell lysates, immunohistochemical localization on paraformaldehyde- or formalin-fixed tissue sections, and immunofluorescence imaging on cultured cells and cryosections. Each vial contains 100 µl of unconjugated antiserum, and the antibody has been characterized on human samples in the contexts of group II mGluR pharmacology, neurodegenerative disease research, and glioma biology, where it is used to identify GRM3-positive cell populations and to monitor expression changes downstream of pharmacological or genetic perturbation.