Anti-GRM1 Antibody

From Antibodies.com, this rabbit polyclonal IgG antibody targets the metabotropic glutamate receptor 1 (GRM1/mGluR1) for research applications involving human samples. Validated for western blot and immunohistochemistry, the unconjugated reagent is supplied as a 200 µl vial of polyclonal IgG, providing flexibility in secondary antibody choice and detection chemistry. GRM1 is a G-protein coupled receptor central to glutamatergic signaling in the central nervous system, and it has been studied in neuronal plasticity research as well as in melanoma and other cancers where ectopic GRM1 expression drives aberrant signaling. Researchers investigating receptor trafficking, synaptic localization, or oncogenic glutamate signaling pathways apply this reagent to probe endogenous GRM1 expression in tissue sections and cell lysates. The antibody is reactive with human GRM1, making it a useful tool for studies on human cell lines and tissue specimens.