Anti-GRM1 Antibody

Human metabotropic glutamate receptor 1 (GRM1, mGluR1) is targeted by this unconjugated polyclonal IgG antibody raised in rabbit and distributed by Antibodies.com. The reagent is supplied as a 100 µl vial validated for western blot and immunohistochemistry applications. GRM1 is a 7-transmembrane G protein-coupled receptor coupled to Gq that activates phospholipase C signaling and mediates slow excitatory glutamatergic transmission in the central nervous system. It is a research focus in cerebellar function studies and in melanoma biology, where ectopic GRM1 expression has been linked to tumor growth. The antibody reacts with the human protein, and the polyclonal format supports detection of multiple epitopes on the target. Store at -20°C and aliquot to limit freeze-thaw cycles. For research use only.