Anti-GRM1 Antibody

Rabbit polyclonal antibody targeting GRM1 (metabotropic glutamate receptor 1, mGluR1), a G protein-coupled receptor central to glutamatergic signaling in the central nervous system. This unconjugated primary reagent from Antibodies.com is validated for Western blot and immunohistochemistry workflows on human, mouse, and rat samples, supporting studies of cerebellar circuitry, synaptic plasticity, and neurological disease models.

Each vial is supplied as 100 µl of polyclonal serum raised in rabbit, intended for research use only. The antibody has been used to map receptor expression in brain tissue and to investigate aberrant mGluR1 signaling linked to melanoma and certain neurodevelopmental disorders. Recommended handling includes brief equilibration to room temperature before use, with long-term storage frozen in working aliquots to limit freeze-thaw cycles of the stock.

Researchers studying mGluR1-mediated signaling, group I metabotropic glutamate receptor pharmacology, or GRM1 expression in neuronal and tumor models will find this reagent useful for immunoblotting of cell and tissue lysates as well as IHC on fixed sections. Each lot ships with host, clonality, conjugate status, and reactivity information detailed on the accompanying datasheet.