Anti-GRK1 Antibody

Offered by Antibodies.com, this affinity-purified polyclonal reagent is raised in rabbit against a synthetic peptide derived from human GRK1 (G protein-coupled receptor kinase 1), enabling detection of the endogenous target in retinal and phototransduction research workflows. The antibody is supplied as an unconjugated preparation at 1.0 mg/mL in a 50 µl volume, buffered in phosphate-buffered saline (without Mg²⁺ and Ca²⁺) at pH 7.4, containing 150 mM NaCl, 0.02% sodium azide and 50% glycerol as a cryoprotectant. It has been validated by the supplier for Western blotting (WB) and immunohistochemistry (IHC), and it cross-reacts with human, mouse and rat samples, making it suitable for comparative expression studies across mammalian model systems. The polyclonal format allows recognition of multiple epitopes on GRK1, supporting robust signal in both denaturing lysate assays and fixed-tissue staining. For handling, the vial is shipped at 4 °C and should be aliquoted upon arrival and stored at –20 °C, with repeated freeze/thaw cycles avoided to preserve antibody activity. Researchers characterising rhodopsin regulation, GPCR desensitisation, or retinal disease mechanisms will find this reagent a reliable tool for both routine blotting and tissue-localisation experiments.