Anti-GRIN3B Antibody

This rabbit polyclonal IgG preparation targets the glutamate ionotropic receptor NMDA type subunit 3B (GRIN3B), an auxiliary NMDA receptor subunit expressed predominantly in central nervous system neurons. Provided by Antibodies.com as an unconjugated primary antibody, the reagent is supplied in a 200 µL vial and validated for Western blot detection of rat GRIN3B.

GRIN3B is a developmentally regulated subunit that modulates NMDA receptor properties by incorporating into receptor complexes, with notable expression in motor neurons during embryonic stages and more restricted distribution in adult tissue. Researchers studying NMDA receptor composition, glutamatergic signaling, or motor neuron biology can apply this polyclonal reagent to detect endogenous GRIN3B protein in rat tissue lysates and primary neuron cultures prepared under standard denaturing and reducing conditions.

The antibody is shipped refrigerated and should be stored at -20 degrees C for long-term use, with working aliquots prepared to limit freeze-thaw cycles. The polyclonal nature of the reagent allows recognition of multiple epitopes on the target, which can be useful when probing for full-length GRIN3B or when working with samples that may contain truncated splice variants.

This unconjugated IgG reagent is intended for research use only and pairs cleanly with HRP- or fluorophore-conjugated secondary antibodies for chemiluminescent or fluorescent Western blot imaging of rat brain, spinal cord, and cultured neuron samples. Each batch is quality controlled to confirm reactivity against the GRIN3B target in the indicated species.