Anti-GRID2 Antibody

Raised in rabbit against Glutamate Ionotropic Receptor Delta Type Subunit 2 (also known as GluD2 or GluRδ2), this unconjugated polyclonal antibody from Antibodies.com targets a delta-family ionotropic glutamate receptor that is most strongly expressed in cerebellar Purkinje cells and governs parallel-fiber synapse formation, motor learning, and cerebellar plasticity. The reagent is supplied as 100 µL of ready-to-use solution and is validated for Western Blot (WB) and Immunofluorescence (IF) applications on human, mouse, and rat samples.

GRID2 immunolabeling is broadly used in neuroscience research on cerebellar ataxia, spinocerebellar degeneration, Purkinje-cell development, and motor-coordination models. Researchers apply the antibody to transfected cell lines, primary neuronal cultures, and brain-tissue lysates to characterize protein expression, and to fixed cerebellar sections to localize the receptor at parallel-fiber/Purkinje-cell synapses. The polyclonal format provides multi-epitope recognition, supporting clear signal on denatured Western blot membranes and on fixed tissue for IF imaging.

For handling, store the antibody refrigerated at 4 °C for short-term use, or freeze at -20 °C in single-use aliquots to limit freeze-thaw cycles and preserve binding activity over time. Each lot from Antibodies.com is quality-controlled to confirm specificity for the human, mouse, and rat GRID2 orthologs.