Anti-GRIA3 Antibody

This polyclonal reagent targets GRIA3 (also called GluA3), an AMPA receptor subunit investigated in excitatory synaptic transmission and glutamatergic signaling research. Raised in rabbit and supplied by antibodies.com as an unconjugated 100 µl aliquot at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the antibody is validated for Western blot, immunohistochemistry, and immunofluorescence workflows on human, mouse, and rat samples.

GRIA3 contributes to AMPA receptor assembly and trafficking at the postsynaptic membrane, where it shapes desensitization kinetics and calcium permeability of the tetrameric channel. Researchers use the antibody to map subunit expression across hippocampal and cortical regions, monitor receptor redistribution in long-term plasticity assays, and characterize changes in glutamatergic signaling associated with epilepsy models, Rasmussen's encephalitis, and broader neurodegeneration studies. The 50% glycerol formulation also allows convenient storage at -20 °C with minimal freeze-thaw damage across repeated experimental cycles.