Anti-GPS1 Antibody

This rabbit polyclonal IgG reagent from Antibodies.com is raised against the GPS1 protein, the ~56 kDa subunit 1 of the COP9 signalosome complex that regulates cullin-RING E3 ubiquitin ligase activity through deneddylation of cullins. Synonymous gene names include COPS1 and CSN1, and the protein is also referenced as JAB1-containing signalosome subunit 1. Supplied as unconjugated antiserum in a 100 µl vial, the reagent supports western blot detection of endogenous GPS1 in mouse cell and tissue lysates, with mouse confirmed as the validated reactivity species. The unconjugated format leaves conjugation open for HRP, biotin, or fluorescent dye labelling downstream of the primary incubation, so laboratories can adapt the reagent to chemiluminescent or fluorescent immunoblot pipelines. Researchers studying COP9 signalosome assembly, cullin neddylation cycles, or JNK cascade regulation will find this antibody relevant to experiments probing deneddylation dynamics and signalosome composition. Recommended handling is to store at -20 °C in small aliquots, with freeze-thaw cycles kept to a minimum to preserve antibody binding activity across multiple western blot experiments.