Anti-GPR50 Antibody

Raised in rabbit against the human GPR50 orphan G-protein coupled receptor, this unconjugated polyclonal antibody from Antibodies.com supports detection of the receptor in central nervous system and peripheral tissues. GPR50 is notable for its unusually long cytoplasmic tail, its capacity to heterodimerize with melatonin receptors MT1 and MT2, and reported associations with thermoregulation, feeding behavior, and affective disorders including bipolar disorder. Researchers apply this reagent to western blot, immunofluorescence, and ELISA workflows to investigate receptor expression, subcellular localization, and signaling interactions.

Supplied as 100 µl of polyclonal antiserum in a vial, the reagent is intended for research use only. The unconjugated format allows flexible pairing with secondary reagents for chromogenic, fluorescent, or HRP-based detection. Human reactivity is indicated; performance on other species has not been characterized. For storage, refrigerate the vial upon receipt and avoid repeated freeze-thaw cycles to preserve antibody titer and binding activity across multiple experiments.