Anti-GPR38 Antibody

Antibodies.com offers this rabbit polyclonal antibody targeting GPR38 (also known as GPBAR1 or TGR5), a membrane-bound G protein-coupled receptor activated by bile acids such as lithocholic acid. The unconjugated format allows flexibility for downstream detection workflows, while the polyclonal nature provides broader epitope coverage suitable for detecting endogenous receptor expression across multiple species.

This primary antibody is validated for Western blot applications and shows reactivity against human, mouse, and rat samples. It is supplied at 1 mg/ml in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.2, packaged in a 100 µl vial. Researchers investigating bile acid signaling, metabolic regulation, or GPCR-related pathways commonly rely on this reagent for expression profiling studies.

GPR38/GPBAR1 plays roles in energy homeostasis, glucose metabolism, and inflammatory responses, making it a target of interest in metabolic disease research. The polyclonal antibody format supports detection of multiple epitopes on the receptor, which can improve signal in Western blot assays. Aliquot upon receipt and store refrigerated to preserve antibody activity across multiple experiments.