Anti-GPR182 Antibody

Raised in rabbit against the human and murine GPR182 receptor, this unconjugated polyclonal antibody targets an atypical G-protein coupled receptor originally characterized as an adrenomedullin-binding locus and now implicated in lymphatic endothelial development. The reagent is validated for Western blot and immunohistochemistry workflows, supporting detection of endogenous receptor levels in tissue sections and lysates prepared from human and mouse samples. Supplied as 100 µl of liquid antiserum, the preparation is appropriate for both chromogenic IHC on fixed specimens and immunoblotting of membrane and cytosolic fractions, and pairs cleanly with standard HRP-conjugated secondary reagents. Investigators studying lymphatic vessel patterning, adrenomedullin signaling, and related angiogenic pathways use this reagent to map receptor distribution across normal and tumor-associated vasculature, where altered GPR182 expression has been reported in published models. Each lot is produced under the Antibodies.com quality program and ships refrigerated to preserve antibody activity over the intended shelf life.