Anti-GPR171 Antibody

GPR171 Neuropeptide Receptor Antibody for Receptor Signaling Studies

From Antibodies.com, this rabbit polyclonal antibody targets GPR171, a G-protein coupled receptor that was deorphanized in 2013 as the binding partner for the proSAAS-derived neuropeptide BigLEN. The receptor is broadly expressed throughout the central nervous system, with notable enrichment in the hypothalamus, and has been linked to feeding behavior regulation, anxiety-like responses, and pain and itch signaling in rodent models.

Provided as 100 µl of unconjugated antibody at 1 mg/ml in phosphate buffered saline (PBS, pH approximately 7.2) supplemented with 0.05% sodium azide as a preservative. The antibody has been validated for Western blot (WB) and immunofluorescence (IF) applications across human, mouse, and rat samples, supporting cross-species expression studies of this neuropeptide receptor in brain and peripheral tissues.

Polyclonal rabbit host format allows recognition of multiple epitopes on the GPR171 protein, useful for studies of receptor localization in transfected cell lines, primary neuronal cultures, and tissue sections.