Anti-GPR124 Antibody

Raised in rabbit against the GPR124 adhesion G-protein coupled receptor, this unconjugated polyclonal reagent from Antibodies.com is supplied as 100 µl of ready-to-use antibody optimized for western blot and immunohistochemistry workflows.

GPR124, also called TEM5 or ADGRA2, is a cell-surface receptor enriched on endothelial cells, where it cooperates with Wnt7a/7b ligands to drive blood-brain barrier induction and central nervous system angiogenesis.

Researchers investigating tumor neovascularization, vascular development, neurovascular biology, and BBB integrity rely on this reagent to detect endogenous GPR124 in human and mouse tissue samples, with confirmed reactivity against both species.

The unconjugated format allows pairing with HRP-, biotin-, or fluorophore-conjugated secondary antibodies for chromogenic or immunofluorescence detection on frozen sections, paraffin-embedded specimens, and standard immunoblotting membranes.

For best results, store refrigerated and protect from light, aliquoting to limit freeze-thaw cycles and preserve antibody activity across multiple experiments.