Anti-GPR112 Antibody

This rabbit polyclonal reagent from Antibodies.com is raised against GPR112, an orphan adhesion-type G protein-coupled receptor (also designated ADGRG3) that has attracted research interest for its tissue-restricted expression pattern and emerging links to tumor biology. The antibody is supplied as 100 µl of liquid at 1 mg/ml in phosphate buffered saline (pH approximately 7.2) containing 0.05% sodium azide as a preservative, and it is unconjugated so it can be paired with the secondary detection reagent of the user's choice.

It is validated for Western blot and has been tested for reactivity against human, mouse, and rat samples, supporting cross-species expression studies. The polyclonal format recognises multiple epitopes on the target, which can be useful when working with samples where a single monoclonal epitope may be lost due to degradation or post-translational modification. Aliquot upon receipt to minimise repeated freeze-thaw cycles and keep refrigerated in the dark to preserve activity.

Researchers studying GPCR signalling, receptor expression in normal versus diseased tissue, or screening candidate biomarkers commonly pair this reagent with appropriate loading controls and HRP- or fluorophore-conjugated secondary antibodies for chemiluminescent or fluorescent detection.