Anti-GPER1 Antibody

GPER1 (G Protein-Coupled Estrogen Receptor 1) is a seven-transmembrane receptor that mediates rapid, non-genomic estrogen signaling across breast, ovarian, uterine, cardiovascular, and neural tissues. This primary antibody from Antibodies.com is raised in rabbit against the receptor and is supplied as 100 µl of unconjugated polyclonal antisera.

Validated for Western Blot (WB) and Immunohistochemistry (IHC) on human samples, the reagent recognizes multiple epitopes on GPER1, which helps when individual epitopes are masked by post-translational modification or aldehyde fixation in archival tissue. The unconjugated format allows flexible pairing with HRP-, biotin-, or fluorophore-conjugated secondary antibodies to match laboratory detection chemistries.

Typical research uses include profiling GPER1 expression in estrogen-responsive cancers, studying membrane-initiated steroid signaling in cardiovascular and neuroscience models, and validating transcriptomic findings for GPER1 at the protein level.

For handling, aliquot upon receipt and store refrigerated at 4 °C; protect from light and avoid repeated freeze-thaw cycles. Research use only.