Anti-GPC1 Antibody

GPC1 (Glypican-1) is a GPI-anchored heparan sulfate proteoglycan that participates in growth factor signaling and has drawn considerable attention as a biomarker candidate in pancreatic cancer exosome research. This unconjugated Rabbit polyclonal reagent from Antibodies.com was raised against the human GPC1 target and is validated for Western blot and immunohistochemistry on Human samples.

The antibody ships as a 100 µl liquid aliquot, sufficient for multiple rounds of staining and blotting experiments at standard working dilutions. In WB workflows, the reagent detects the full-length glypican core protein, while in IHC it supports localization studies in formalin-fixed tissue sections where altered GPC1 expression has been linked to tumor biology and developmental signaling pathways including Wnt and FGF.

Because GPC1 is a cell-surface proteoglycan rather than a secreted cytokine, the reagent also fits downstream workflows such as immunoprecipitation of membrane fractions, characterization of circulating extracellular vesicles, and pathway-focused studies of growth-factor-driven signaling in research use only settings.