Anti-GP IIb/IIIa Antibody [Y8]

This mouse monoclonal IgG1 antibody from Antibodies.com targets the platelet integrin GP IIb/IIIa, the fibrinogen receptor central to platelet aggregation and thrombus formation. Clone Y8 was raised against the human complex and is reactive with human samples, making it useful in cardiovascular, hematology, and thrombosis research workflows. The unconjugated reagent is supplied as 100 µg of lyophilised material, allowing flexible reconstitution and long-term storage. It is validated for ELISA and Western blot, supporting detection of the target in platelet lysates, whole-cell extracts, and purified integrin preparations. Researchers working on integrin signalling, platelet activation markers, or antiplatelet drug effects can apply this reagent for immunoblotting of the GP IIb/IIIa heterodimer under reducing or non-reducing conditions. As an IgG1 isotype, it is compatible with standard anti-mouse secondary reagents across common immunodetection chemistries.