Anti-GP IIb/IIIa Antibody [128]

A mouse monoclonal IgG1 reagent from Antibodies.com, clone 128, targets the platelet fibrinogen receptor GP IIb/IIIa (integrin αIIbβ3). This receptor governs platelet aggregation by bridging activated platelets through fibrinogen and von Willebrand factor, and it is a focus of cardiovascular, thrombosis, and antiplatelet-drug research. Reactive with the human complex, the antibody supports studies of platelet activation, integrin conformation, and inherited or acquired platelet disorders such as Glanzmann thrombasthenia and immune thrombocytopenia.

Supplied as 100 µg of lyophilised powder from Antibodies.com, the antibody reconstitutes for use in ELISA and related immunoassays and is unconjugated for flexible pairing with HRP, biotin, or fluorophore reporters. Researchers handling platelet-rich plasma, washed platelet suspensions, or platelet lysates can apply the reagent in receptor-occupancy assays, inhibition studies with candidate antagonists, and characterisation of patient samples. The unconjugated IgG1 format is also compatible with custom biotinylation or fluorophore conjugation workflows when direct readout of platelet-bound antibody is required.