Anti-GOT2 Antibody

This rabbit polyclonal antibody from Antibodies.com targets GOT2, the mitochondrial isoform of glutamic-oxaloacetic transaminase (also called aspartate aminotransferase 2). GOT2 resides in the mitochondrial matrix and contributes to the malate-aspartate shuttle, which transfers reducing equivalents across the inner mitochondrial membrane, and it also feeds carbon skeletons into the urea cycle.

Provided as 100 µl of unconjugated antiserum in a vial, the reagent is validated for Western blot and immunohistochemistry workflows. It reacts with human and mouse samples, supporting studies in cell lines, primary tissue sections, and rodent disease models where mitochondrial metabolism, hepatic function, or aspartate-driven nucleotide synthesis are being investigated.

Researchers commonly apply the antibody to confirm expression of GOT2 in hepatocytes, cardiac tissue, and several tumor types. Storage guidance includes aliquoting upon arrival and freezing to limit freeze-thaw cycles, preserving binding activity across repeated experiments.