Anti-GNL3 Antibody

This rabbit polyclonal primary antibody from Antibodies.com targets GNL3, a nucleolar GTP-binding protein also referred to as Nucleostemin (NS) that is enriched in embryonic stem cells, neural progenitors, and a broad set of proliferating cancer cell lines. The unconjugated reagent is supplied as 100 µL of antiserum and is validated for Western blot and immunohistochemistry on human samples, supporting studies of ribosome biogenesis, cell-cycle progression, and p53 pathway regulation where nucleostemin functions as a stemness and proliferation marker.

Because GNL3 expression is sharply down-regulated on differentiation and re-activated in many tumours, the reagent is frequently cited in oncology and regenerative-biology work exploring nucleolar stress, rRNA processing, and self-renewal. For best results, refrigerate between uses and limit freeze-thaw cycles to preserve polyclonal reactivity.