Anti-GNL3 Antibody

Raised in rabbit against human GNL3 (guanine nucleotide-binding protein-like 3, also known as nucleostemin), this unconjugated polyclonal antibody from Antibodies.com binds a nucleolar GTPase involved in ribosome biogenesis, stem-cell proliferation, and p53 pathway regulation.

Validated for western blot and immunohistochemistry on human specimens, the reagent is supplied as 100 µl of liquid at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol. The glycerol-rich formulation helps preserve activity during frozen storage and tolerates repeated freeze-thaw cycles when the solution is aliquoted before use; working stocks are best kept refrigerated and protected from light.

Investigators studying cancer stem-cell markers, nucleolar stress responses, or cell-cycle checkpoint control will appreciate the polyclonal format, which offers broader epitope coverage than a monoclonal reagent when probing endogenous GNL3 levels in human tissue lysates and fixed sections.