Anti-GNB4 Antibody

GNB4 encodes the beta-4 subunit of heterotrimeric G proteins, a core component of the G-protein coupled receptor signaling cascade that couples receptor activation to downstream effectors. Mutations in this gene have been linked to Charcot-Marie-Tooth disease type 2J, a dominantly inherited axonal peripheral neuropathy.

This unconjugated rabbit polyclonal IgG reagent from Antibodies.com is raised against human GNB4 and validated for Western blot detection of the endogenous protein. The antibody is supplied as 100 µL of liquid, suitable for standard immunoblotting workflows that resolve GNB4 from cell or tissue lysates.

For long-term preservation, aliquoting upon receipt and storing at -20°C is recommended, with brief removal of working aliquots to limit freeze-thaw cycles and maintain reactivity across experiments.