Anti-GNAS Antibody

Offered by Antibodies.com, this affinity-purified reagent is a Rabbit polyclonal antibody raised against a recombinant human GNAS immunogen and validated for the detection of endogenous total GNAS protein. Supplied at 1.0 mg/mL in a 50 µl volume, the preparation is formulated in phosphate-buffered saline (pH 7.4) containing 150 mM NaCl, 0.02% sodium azide, and 50% glycerol, and ships unconjugated for maximum flexibility in downstream assay design. The antibody is recommended for Western blotting (WB) and immunocytochemistry/immunofluorescence (ICC/IF) workflows and has been verified to react with Human, Mouse, and Rat samples, making it a versatile choice for cross-species signaling studies of the Gα subunit encoded by the GNAS locus (also known as GNAS1 or GSP). Storage is straightforward: the vial is shipped at 4 °C and, upon arrival, should be aliquoted and frozen at −20 °C, with repeated freeze/thaw cycles avoided to preserve activity. As a polyclonal reagent generated in Rabbit, the product provides epitope redundancy that is particularly useful when probing for isoforms such as the adenylate cyclase-stimulating G alpha protein. It is intended for research use only and is not validated for diagnostic or therapeutic applications.