Anti-GNAI3 Antibody

The GNAI3 protein is a member of the inhibitory G-protein alpha subunit family, acting on adenylate cyclase signaling cascades to modulate downstream effector activity across many cell types. This Rabbit polyclonal IgG preparation from Antibodies.com is supplied unconjugated as 100 µl of antiserum-derived reagent, raised against the GNAI3 target. It is validated for Western blot and immunohistochemistry workflows and reacts with human, mouse, and rat samples, allowing consistent use of one reagent across multiple model systems.

Because the antibody is unconjugated, laboratories can attach their own HRP, biotin, or fluorophore label depending on whether they plan chromogenic or immunofluorescence detection. Researchers studying G-protein coupled receptor (GPCR) signaling, neurotransmitter response pathways, and tumor biology contexts use this reagent to probe GNAI3 distribution in tissue sections and whole-cell lysates; the polyclonal composition means multiple epitopes are recognized simultaneously, which tends to improve signal-to-noise in formalin-fixed paraffin-embedded sections and standard immunoblotting membranes.

Aliquot on first use to preserve freeze-thaw tolerance, and store the vial at -20 °C between sessions; avoid repeated freeze-thaw cycles. Brief centrifugation clears any aggregated material without depleting the active IgG fraction.