Anti-GNA13 Antibody

Targeting the alpha-13 subunit of heterotrimeric G proteins (GNA13 / Gα13), this unconjugated polyclonal IgG reagent from Antibodies.com recognizes a 44 kDa GTPase that couples G-protein-coupled receptors to RhoA activation, cytoskeletal remodeling, and cell migration pathways. The 200 µl liquid preparation in buffered solution lets users pair it with a labeled secondary antibody of their choice for flexible detection chemistry across standard immunodetection workflows.

Raised in rabbit and validated for Western blotting, immunohistochemistry, and immunofluorescence on human, mouse, and rat samples, the antibody supports detection of endogenous Gα13 in cell lysates, paraffin or frozen tissue sections, and fixed-cell imaging preparations. Studies of Rho-mediated cytoskeletal dynamics, cell adhesion, and downstream GPCR signaling benefit from the reagent's compatibility with conventional immunostaining protocols.

From Antibodies.com, each lot is affinity-purified, and the polyclonal profile broadens epitope coverage across the target. Handling recommendations such as aliquoting to limit repeated freeze-thaw cycles help preserve activity across multiple experimental setups.