Anti-GNA11 Antibody

Raised in rabbit and affinity-purified, this polyclonal reagent from Antibodies.com targets GNA11, the gene that encodes the G protein subunit alpha-11 (Gα11), a heterotrimeric Gq-family α subunit that couples phospholipase Cβ activation and intracellular calcium mobilization to G-protein-coupled receptor signaling.

The antibody is supplied as a 100 µl aliquot at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, and is unconjugated for flexible pairing with HRP, fluorophore, or biotin secondaries. It is validated for Western blot and immunohistochemistry on human, mouse, and rat samples, supporting work on melanoma driver mutations, Gq-coupled receptor pharmacology, and downstream phospho-PLCβ or calcium flux readouts.