Anti-GMNN Antibody

This rabbit polyclonal antibody from Antibodies.com targets Geminin (GMNN), a nuclear protein that regulates DNA replication licensing by binding and inhibiting CDT1, preventing re-replication during a single cell cycle. Geminin expression rises through S and G2 and is targeted for proteasomal destruction by the APC/C complex during mitosis, which makes it a useful marker for cell cycle progression studies in proliferating populations.

The unconjugated reagent is supplied at 1 mg/ml in PBS with 0.1% Sodium Azide and 50% Glycerol as a 100 µl vial, validated for Western blot (WB) and immunohistochemistry (IHC) workflows. Reported reactivity covers Human, Mouse, and Rat samples, supporting cross-species investigations in cancer biology, neurodevelopment, and stem cell differentiation research. The glycerol-containing formulation helps preserve antibody activity through repeated freeze-thaw cycles; aliquoting on receipt is recommended to limit handling of the original stock.