Anti-GM2A Antibody

This unconjugated rabbit polyclonal reagent enables detection of ganglioside GM2 activator protein in human and mouse research samples. GM2A supports lysosomal GM2 ganglioside turnover by presenting the lipid substrate to β-hexosaminidase A, making the antibody relevant to studies of lysosomal lipid catabolism, ganglioside metabolism, and altered GM2A expression in experimental models.

The applications listed for this Antibodies.com antibody are western blot and immunohistochemistry. Western blot can be used to assess GM2A abundance in prepared protein extracts after electrophoretic separation and membrane transfer. Immunohistochemistry supports protein localization studies in fixed tissue sections when combined with a suitable detection system. Its unconjugated format allows researchers to select compatible enzyme-labeled, fluorescent, or other secondary reagents for their preferred workflow.

Raised in rabbit, this polyclonal antibody comprises immunoglobulins targeting multiple epitopes on GM2A rather than a single defined clone. Reported reactivity covers human and mouse specimens. The supplied volume is 100 µl, and the working dilution should be optimized for the specific lysate, tissue preparation, membrane-transfer or fixation procedure, secondary reagent, and detection method. Appropriate positive and negative controls should accompany each experiment when comparing GM2A expression or localization.