Anti-GLYCTK Antibody

GLYCTK (glycerate kinase) is a mitochondrial enzyme that phosphorylates D-glycerate to 3-phosphoglycerate, positioning the protein at a metabolic crossroads between serine catabolism and fructose metabolism. Loss-of-function mutations in the gene are linked to D-glyceric aciduria, which makes reliable detection reagents valuable for metabolic and mitochondrial research. This unconjugated rabbit polyclonal IgG reagent from Antibodies.com is raised against human glycerate kinase and shows cross-reactivity with mouse and rat orthologues, supporting comparative work across standard mammalian model systems.

Provided as 200 µL of liquid antibody in a single vial, the reagent is validated for Western blot detection of endogenous GLYCTK in cell and tissue lysates following standard SDS-PAGE separation and transfer. Because the antibody is unconjugated, researchers can pair it with HRP- or fluorophore-conjugated secondary reagents of their choice to fit established immunoblotting workflows.

For handling, aliquot the antibody upon arrival into single-use portions and store frozen at -20 °C to limit freeze-thaw cycles and preserve reagent activity. Protect from light and keep on ice during active bench use. This polyclonal reagent is intended for research use only and is supplied as 200 µL of ready-to-dilute liquid in a vial.