Anti-glycerol kinase 2 Antibody

Raised in rabbits against glycerol kinase 2, this unconjugated polyclonal reagent from Antibodies.com is supplied as a 100 µl aliquot and is validated for Western blot, immunohistochemistry, and immunofluorescence workflows on human samples.

Glycerol kinase 2 (GK2) is a mitochondrial outer-membrane enzyme that catalyzes the ATP-dependent phosphorylation of glycerol to glycerol-3-phosphate, connecting carbohydrate catabolism with glycerolipid biosynthesis and triglyceride synthesis. Researchers profile endogenous GK2 to investigate hepatic and adipocyte lipid handling, mitochondrial enzyme localization, and the contribution of glycerol metabolism to insulin signaling and energy homeostasis. Relevant applications include probing cell lysates from metabolic cell models, staining fixed liver and adipose tissue sections, and visualizing mitochondrial-associated GK distribution in cultured cells.

The unconjugated format permits flexible pairing with user-selected secondary reporters for chromogenic or fluorescence multiplexing. Storage at -20 °C in working aliquots preserves binding activity across repeated freeze-thaw cycles, and the small-format vial size suits pilot studies and limited sample cohorts.