Anti-GluR1 Antibody

Raised in rabbit and unconjugated, this polyclonal antibody from Antibodies.com recognizes the GluR1 (GluA1) subunit of the AMPA-type ionotropic glutamate receptor, which is highly expressed at excitatory synapses throughout the central nervous system. The reagent is provided at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol, supplied as a 100 µl vial suitable for multiple experiments in neuroscience research.

Validated for western blot, immunofluorescence, and immunohistochemistry on human, mouse, and rat samples, the antibody supports studies of AMPA receptor trafficking during long-term potentiation, synaptic plasticity underlying learning and memory, and remodeling of glutamatergic circuitry in neurodegenerative disease models. GluR1 is also a key marker in research on phosphorylation-dependent regulation at residues such as Ser831 and Ser845.

Storage at -20°C in the supplied glycerol buffer preserves antibody activity, and aliquoting on first use minimizes freeze-thaw damage over extended projects. Each vial is intended for research use only and fits standard western blot, immunofluorescence, and immunohistochemistry workflows in academic and pharmaceutical neuroscience laboratories.