Anti-GLUL Antibody

Generated for research laboratories, this unconjugated rabbit polyclonal reagent targets GLUL, the gene encoding glutamine synthetase — an ATP-dependent ligase that converts glutamate and ammonia into glutamine. Supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the antibody is packaged as a 100 µl vial and validated for western blot, immunohistochemistry, and immunofluorescence workflows across human, mouse, and rat sample types. Glutamine synthetase plays a central role in nitrogen homeostasis, ammonia detoxification in the liver, and neurotransmitter recycling in brain astrocytes, making this reagent relevant for neuroscience, hepatic biology, and cancer metabolism studies where glutamine dependency is a topic of investigation. Storage at -20 °C in single-use aliquots helps preserve activity and minimize freeze-thaw damage to the polyclonal preparation. Researchers commonly deploy this reagent to probe astrocyte markers in brain tissue sections, examine periportal hepatocyte zonation in liver samples, and assess glutamine synthetase expression in tumor models. The unconjugated format allows flexible pairing with HRP, biotin, or fluorophore-labeled secondary reagents of the user's choice. Each lot is produced by Antibodies.com as a primary antibody reagent for research use only, supporting reproducible detection of the ~42 kDa glutamine synthetase protein in cell and tissue lysates.