Anti-GLRA1 Antibody

Raised in rabbit against the glycine receptor alpha 1 subunit, this polyclonal IgG reagent from Antibodies.com targets an inhibitory ligand-gated chloride channel encoded by the GLRA1 gene and predominantly expressed in the brainstem and spinal cord. Loss-of-function mutations in GLRA1 are linked to hereditary hyperekplexia, supporting its use in studies of glycinergic signaling and motor control circuitry.

The unconjugated antibody is supplied as 50 µl of liquid stock and is validated for Western blot (WB) on human, mouse, and rat samples. The polyclonal format recognizes multiple epitopes on the target, helping generate a clear band near the expected molecular weight of the receptor subunit in immunoblotting workflows.

Intended for research use only, the reagent is suited to neuroscience and neuropharmacology laboratories investigating channelopathies, inhibitory synapse biology, or developmental expression patterns of inhibitory receptors in the central nervous system.