Anti-GLP2R Antibody

Raised in rabbit against the human glucagon-like peptide 2 receptor, this polyclonal primary antibody from Antibodies.com targets a class B G protein-coupled receptor best known for driving intestinal epithelial proliferation, mucosal repair, and nutrient absorption downstream of GLP-2 signaling.

Provided as 100 µl of unconjugated IgG, the reagent is validated for Western Blot detection of GLP2R in human and mouse samples, supporting studies of intestinal adaptation following resection, inflammatory bowel disease models, and metabolic research into how GLP-2 analogs such as teduglutide engage their endogenous receptor.

Because the antibody is polyclonal, it recognizes multiple epitopes across GLP2R, which often improves signal recovery on Western Blot when antigen levels are modest or when working with partially denatured lysates. Common sample inputs include intestinal mucosal scrapings, subepithelial myofibroblast cultures, or transfected cell lines overexpressing recombinant GLP2R, separated by SDS-PAGE and probed with the antibody at a working dilution appropriate for chemiluminescent detection.

Aliquot upon first use and store at -20 °C for long-term stability, avoiding repeated freeze-thaw cycles that can compromise IgG integrity. The unconjugated format leaves secondary antibody choice open to the end user, whether HRP-linked for chemiluminescence or a fluorophore conjugate for multiplex fluorescence Western Blot.