Anti-GLK Antibody

This Rabbit polyclonal antibody from Antibodies.com targets GLK, also known as MAP4K3, a serine/threonine kinase that participates in amino acid sensing and signaling upstream of the mTORC1 pathway. The unconjugated reagent is supplied as a 100 µl volume at 1 mg/ml in PBS with 0.1% Sodium Azide and 50% glycerol, a buffer system chosen to limit freeze-thaw damage and maintain reagent activity during routine bench handling.

Validated for Western blot and immunohistochemistry workflows, the antibody shows reactivity with Human, Mouse, and Rat samples, supporting comparative studies across model organisms in immunology, signal transduction, and oncology laboratories. Researchers use it to probe GLK involvement in T-cell receptor signaling, nutrient-dependent growth control, and inflammatory disease models where kinase expression is being mapped at the tissue level.

As a polyclonal reagent, the antibody binds multiple epitopes on the GLK protein, which can enhance signal recovery when target abundance is low. The unconjugated format leaves the labeling step open, so investigators can pair the antibody with HRP, biotin, or fluorophore conjugates to suit their preferred detection chemistry. Aliquoting upon first use and storage at -20°C is recommended to preserve binding performance across repeated experiments.