Anti-GLB1 Antibody

Lysosomal beta-galactosidase research benefits from a polyclonal reagent validated for Western blot detection of GLB1 across human and rat samples. This rabbit antibody, supplied by Antibodies.com as an unconjugated IgG preparation at 1 mg/ml in phosphate buffered saline with 0.05% sodium azide at approximately pH 7.2, supports investigations into the catabolism of GM1 ganglioside and keratan sulfate, two substrates whose accumulation defines GM1-gangliosidosis and Morquio B disease (MPS IVB).

For routine immunoblotting, aliquot the 100 µl volume upon arrival and store at -20°C, protecting from repeated freeze-thaw cycles to maintain binding activity. The unconjugated format integrates with in vitro workflows that require secondary antibody selection flexibility, including chemiluminescent and fluorescence-based detection of endogenous beta-galactosidase in cell and tissue lysates. The polyclonal nature of the reagent improves recognition of multiple epitopes on the target, increasing tolerance to minor denaturation during SDS-PAGE sample preparation.