Anti-GJC2 Antibody

Raised in rabbit against Gap Junction Protein Gamma 2 (Connexin 47, Cx47), this unconjugated polyclonal IgG is offered by Antibodies.com for protein-level and tissue-localization studies in CNS myelin research. The reagent detects endogenous GJC2 in human, mouse, and rat samples and is validated for Western blot and immunohistochemistry across oligodendrocyte lysates and neural tissue sections.

Supplied as 100 µL of liquid antibody in a vial, the preparation is shipped refrigerated at 4 °C for routine handling. Aliquot and freeze at -20 °C for longer-term storage and limit freeze-thaw cycles to preserve reactivity. The polyclonal format presents multiple epitopes against the 47 kDa transmembrane channel, which is useful when working with truncated or post-translationally modified Connexin 47 isoforms encountered in Pelizaeus-Merzbacher-like disease and spastic paraplegia type 44, where GJC2 mutations underlie white matter pathology and altered glial gap junction coupling during demyelination.