Anti-GJC1 Antibody

GJC1 encodes Connexin 45, a gap junction protein that forms intercellular channels in cardiac and neural tissue, supporting electrical coupling and direct molecular exchange between adjacent cells. The Antibodies.com rabbit polyclonal IgG reagent is raised against the GJC1 target and validated for Western blot and immunohistochemistry workflows on human, mouse, and rat samples, supporting studies in cardiac conduction, neuronal signaling, and gap junction biology. Each vial delivers 50 µl of unconjugated antibody suitable for probing membrane and cytoplasmic connexin distribution in fixed tissue sections and denatured protein lysates. The polyclonal format increases the likelihood of recognizing multiple epitopes on Connexin 45, which can be valuable when expression levels are low or when post-translational modifications vary between samples. Researchers studying arrhythmia mechanisms, glial communication, or developmental patterning where gap junction remodeling plays a role will find this reagent useful for confirming expression changes alongside functional readouts. Store refrigerated and avoid repeated freeze-thaw cycles to preserve activity.